PSYC 3458 Lecture Notes - Lecture 6: Integral Membrane Protein, Gaba Receptor, Chemical Synapse
29 Oct 2017
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Affinity: degree at which a substance tends to combine with another. Agonist: chemical that binds to a receptor and activates the receptor to produce a biological response. Antagonist: receptore or drug that blocks or dampens agonist mediated responses. Neurotransmitte: endogenous ligand that enables cell signaling in the brain, comes in a lot of different flavors. Neuromuscular junction: specialized chemical synapse between motro neuron and skeletal muscle cell. Snare complex: proten that teathers a ca dependent vesicle to the pre synaptic membrane. Acetylcholinesterase: enzyme that catalyzes the breakdown of acetylcholine. Acetylcholine receptor: integral membrane protein that responds to the binding of acetylcholine. Gaba receptor: receptor that responds to neurotransmitter gaba, chief inhibitory neurotransmitter in mature vertebrate cns. Concepts: be able to define, describe and differentiate. Describe the order of steps leading to transmitter release and how transmitters can change postsynaptic membrane potentials. How can the same neurotransmitter have both excitatory and inhibitory effects? (type of receptor)
