BIOL 2301 Lecture Notes - Lecture 26: Pupa, Antennapedia, Hox Gene
15 Sep 2016
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Fertilized egg larval stages pupa metamorphis adult: one cell, one genome multicellular, short time span. Single embryo with thousands of single cell, but same size. Blastoderm: hallow (no cells) of about 6000 cells. Early, synchronous nuclear divisions produce a cluster of nuclei. Embryo converts from single cell to multi: very rapidly: 2 hours. The cells already know what type of cells they will become. Have cells all around edge- all look the same. Already know what part of the body they will lead through signals that change gene expression. Show regions where there are more or less proteins. Patterns of gene expression determine what the cells will become. Make ssdna probe: each different color specific to which mrna it will bind to. Mrna is where the proteins will be hybridize to mrna show where mrnas are overlapping patterns show different colors banding patters establish developmental program. Four levels of gene expression control early drosophila development.
