BIOL 1107 Lecture Notes - Lecture 24: Rna Editing, Open Reading Frame, Alternative Splicing
30 Jan 2018
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Document Summary
Your dna is p much the same in every single cell in your body, the difference occurs in the expression. It"s not just the genes you have, but how are they expressed. Genes do not just get regulated at the promoter stop t. But you can regulate the chromatin remodeling, transcription, rna processing, translation, dna itself. We"re changing the conformation of the dna (the chromatin itself) Chromatin= dna and its associated proteins (ie histones) Epigenetics describes phenomena in which genetically identical cells or organisms express their genomes differently, causing phenotypic diffs. Closed conformation: will physically prevent rna polymerase from getting access to the genes. Genetically identical cells but they have very different phenotypes. Modifications to the dna or to the histone proteins. You can add various functional groups to the amino groups. Depending on the groups you add to the histone tails, you can imagine that the histone tails may more firmly or more loosely hold onto the dna.
