BMS 501 Lecture Notes - Lecture 13: Otitis Externa, Diphtheria Vaccine, Anti-Inflammatory

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Lecture 13: 10/15/15 in oral pharynx you have anaerobic orgs: live in biofilm which protect them from high concentrations of o2. Some can be opportunistic pathogens if they grow outside their niche. Ppl in hospital/ longterm care facilities- enriched for diff orgs that normally don"t live in upper respiratory tract: enterobacteriaceae. Cystic fibrosis and chronic obstructive pulmonary disorder ppl have normal flora that might contribute to their disease. Mucous traps microbes: defends lower respiratory tract. Pharyngitis: inflammation of the throat (pharynx)- general term, streptococcus pharyngitis caused by strepococcus pyogenes, viral pharyngitis, organism is inhaled and adheres to/ colonizes the nasopharynx and oropharynx. Strepococcus pyogenes: normal flora of skin an, you can recognize ur own strepococcus pyogenes bu tyour immune system cannot recognize outside strains leads to illness. Spreads mostly by inhalation: multiplication = extracellular= on surface of tissue, diagnosis: throat or skin culture on blood agar followed gram stain. Left untreated, streptococcal pharyngitis can lead to: bacteremia.

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