MB 351 Lecture 56: 15.6 Immunity and Immunizations
Document Summary
11:26 am: measles is still endemic in comp to outbreaks in 1920, 1 out of 20 causes of death, natural or artificial, naturally active, exposed, ill, recovers from antigen presence. Lifelong immunity (or at least few years: naturally passive, mother to infant antibody transfer, cross placenta. Few months or weeks: essential for immunity until child develops their own, artificially active, vaccination. Injection of antibodies into body: gets antiserum. Serum containing antibodies from blood of immune person: purified antibodies, derived from immune ind. Later had rapid intense response: herd immunity, outbreaks limited to sporadic cases because not enough people are susceptible to support spread, not everyone needs to be immune to it, terminology. Immunization: process of generating artificial active immune resp by exposure to antigen or antigen mixture, most agents are attenuated or inactivated, booster shots are another dose of the same antigen to increase response time.
