MB 351 Lecture 45: 12.3 HIV

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orchidpug565

21 Dec 2018

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First hiv image is sem of immune cell and cd4+ t cell: retroviridae family. Infect vertebrates: reverse transcriptase, viral rna template to make dsdna, end in -viridae, enveloped, hiv. Lentivirus genus: end in -virus, hiv viral species, group of viruses sharing same genetic info and ecological niche, hiv 1 and 2 is subspecies. Final stages of hiv: 9749 nucleotides with two identical ssrna mols, encodes 10 proteins, reverse transcriptase, make dna from rna, degrades original rna. Integrase enzyme incorporates viral dna into host dna: provirus, protected from host immune system, unlike prophage, it never comes out of chromosome. Latent infection: provirus later activated, targets, macrophage, 1st line of dense, t cells, 2nd liane, cd4+ , t helped cells, dendritic cells in mucus areas, monocytes, pre-macrophages. Integrates viral dna to human dna: protease. Sub saharan regions most common: 71% of ppl with hiv live here, 1 in 20 have it, antiretroviral therapy, suppress virus, classes.

Related Questions

1
Which of the following is a component of the HIV virus ?
A
DNA
B
Capsid
C
Nucleus
D
CD4 receptor
Answered
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2
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Homework
2
What is the function of Reverse Transcriptase?
A
To insert the viral RNA into the host DNA.
B
To make an RNA copy of the viral RNA.
C
To make an RNA copy of the viral DNA.
D
To make a DNA copy of the viral RNA.
E
To insert the viral DNA into the host DNA.
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3
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3
Which of the following stages describes a HIV patient in who has a large number of severe opportunistic infections?
A
Primary HIV infection-lasts for a few weeks
B
Clinically asymptomatic stage-lasts for an average of ten years
C
Symptomatic HIV infection
D
Clinical AIDS
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4
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4
Which of the following individuals should be tested for HIV?
A
A newborn child
B
Alex, who studies excessively
C
Sarah, who takes birth control
D
Joe, who uses intravenous steroids
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5
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5
Harry engaged in risky activity that may have lead to exposure to HIV. Two and a half weeks later, he had an HIV test done and it showed a positive result. Which test most likely was done?
A
CD4 test
B
HIV antibody test
C
PCR test
D
Viral load test
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6
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6
How does an Integrase inhibitor work against the HIV virus?
A
It inhibits the generation of viral DNA from viral RNA.
B
It prevents the entry of HIV into the host cell.
C
It inhibits viral proteins from being inserted into new virus particles.
D
It prevents viral DNA from being inserted into host DNA.
E
It prevents the generation of new viral proteins.
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7
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7
How does a Protease inhibitor work to treat HIV infection?
A
It prevents the release of new viral particles.
B
It cleaves viral proteins interfering with their function.
C
It prevents the cleavage of host DNA preventing viral DNA from being inserted into host DNA.
D
It cleaves Reverse transcriptase preventing the generation of viral DNA.
E
It prevents the binding of gp120 to the CD4 protein.
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8
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8
Which of the following describes a combination therapy for HIV infected persons?
A
A preparation used for stimulating a viral response in the body.
B
A single drug given to HIV infected people since interactions with other medications may promote complications in treatment.
C
A drug cocktail-or-combination of antiviral drugs given to HIV infected people since they can be more effective than when given individually
D
A preparation used for stimulating an immune response in the body.
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9
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9
answerable question reference
For HIV to reproduce, which of the following is most critical?
A
Infecting new subjects
B
Producing a Provirus
C
Entering the host cells
D
Taking over the function of DNA in the cell
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10
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10
HIV is a virus which has the following characteristic?
A
It takes of the RNA of the host cell which subsequently by way of transcription and translation makes new virus
B
It attacks the RNA of the host cell causing cellular death
C
It attacks the DNA of the host cell causing cellular death
D
It takes over the DNA of the host cell which subsequently by way of transcription and translation makes new virus

MB 351 Lecture 45: 12.3 HIV

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