NUR 290 Lecture Notes - Lecture 38: Peptic Ulcer, Gastric Pits, Parietal Cell
Document Summary
Pud is ulcer formation in the lining of the upper gi tract that affects mainly the mucosal lining of the stomach, duodenum or esophagus. Three types of peptic ulcers: gastric ulcers: located inside the stomach, duodenum ulcer: located inside the duodenum which is the first part of the small intestine, esophageal ulcer: located inside the lower part of the esophagus. *this lecture will concentrate on gastric and duodenum ulcers. Acid production and breakdown of the defense system of the mucosal lining. Role of the stomach: liquefies the food by churning it and release acids and enzyme such as hcl (hydrochloric acid) and pepsin to break down food. Mucosa: top layer of the mucosa that releases mucous rich in bicarbonate that protects the lining from the stomach acid. It also contains gastric pits that contain the parietal, chief cells, and g-cells: parietal cells: release hydrochloric acid along with intrinsic factor, chief cells: release pepsinogen which mixes with hydrochloric acid and becomes.
