BIOCHM 1090 Lecture Notes - Lecture 20: Carboxypeptidase A, Arginine, Activation Energy

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19 Mar 2018
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2. lower energy barrier for a reaction soluble in aqueous environment (cellular uid: as a general rule. 3. they are not used up in a reaction and they are not changed: water soluble globular proteins. 1. if a substrate is chiral, an enzyme usually catalyzes the reaction of only one of the pair of enantiomers. 2. only one enantiomer ts the active site in such a way that the reaction can occur. E. the catalytic activity of an enzyme is measured by its turnover number. 1. the maximum number of substrate molecules acted upon by one molecule of enzyme per unit time a) turnover number range from 10 to 10,000,000 molecules per second. Enzyme cofactors: an enzyme may require a metal ion, or both. 1. cofactor: a non-protein part of an enzyme that is essential to the enzyme"s catalytic activity a) cofactors can be tightly held or loosely bound, so that they can enter and leave the active site.

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