HNRS 1007 Lecture 4: Energy and Respiration.docx

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17 Oct 2014
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Enzymes: a catalyst is a chemical agent that speeds up a reaction without being consumed by the reaction, an enzyme is a catalytic protein. How enzymes lower the ea barrier: enzymes catalyze reactions by lowering the ea barrier, enzymes do not affect the change in free energy ( g); instead, they speed up reactions that would occur eventually. General environmental factors, such as temperature and ph. Enzyme evolution: altered amino acids in enzymes may alter their substrate specificity, under new environmental conditions a novel form of an enzyme might be favored. Cofactors: cofactors are nonprotein enzyme helpers, cofactors may be inorganic (such as a metal in ionic form) or organic, an organic cofactor is called an coenzyme, coenzymes include vitamins. Enzyme inhibitors: competitive inhibitors, bind to the active site, compete with the substrate, noncompetitive inhibitors, bind away from the active side, decrease activity, examples of inhibitors include, toxins, poisons, pesticides, antibiotics, and many drugs.

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