JAPAN 1 Lecture Notes - Lecture 29: Brainstem, Gyrus, Basal Ganglia

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W. r. : attending physician being ambitious and having a vital social live. Astrocytoma (brain cancer), which cannot be contained -> invaded lateral prefrontal cortex in left hemisphere and parts of right hemisphere, corpus collosum. Behavior: detached, passive, nonchalant, lost his ego & self-drive, lost ability to engage in goal-oriented behavior, problems with making plans. Done with the expected reward in mind, know about connection between behavior and reward. The anatomy behind cognitive control: habit stimulus-driven & automatic triggered simply by external cues, context rapid response, based on well-learned associations. Everything in front of motor cortex (pmc & smc) Expanded compared to other primate species -> bigger white matter, different interconnections. From anterior to posterior: frontral pole (fp) goal related, ventromedial prefrontal cortex/ Orbitofrontal (ofc) control monitoring: lateral prefrontal cortex (lpfc) goal oriented behavior, medial frontal cortex (mfc) guiding & monitoring behavior. Pfc matures late in development -> cognitive control processes acquired late.

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