JAPAN 1 Lecture Notes - Lecture 6: Toyota Racing Development, Amygdala, Striatum

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Can excite or inhibit the brain, allowing researches to find out functionality of brain areas on a millisecond scale. Can be repeated (unlike functional imaging) rtms used to have a positive long-lasting effect on people suffering from long-term- depression (ltd) High-rate rtms (excitatory) applied to left relatively inactive dlpfc may improve depression -> approach. Low-rate rtms (inhibitory) applied to relatively hyperactive right dlpfc -> avoidance. Side effects: might be seizure inducing, even if you do not have epilepsy. Anderson rtms for treatment resistant depression: re-establishing connections: rtms is a non-invasive technique potentially useful for treatment-resistant-depression (trd), and is well-tolerated by patients pathology of depression: Organized in intrinsic connectivity networks (icn), having a coherent function functional connectivity limited by underlying structural connectivity. Default mode network (dmn): ((((includes medial prefrontal cortex, posterior cingulate cortex (pcc), inferior parietal lobe and hippocampal formation))))) Healthy patient: low activity during goal-directed tasks, high activity during self-referential processing and resting-state (daydreaming etc. )

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