DANCEST 805 Lecture Notes - Lecture 16: Allergic Conjunctivitis, Histamine H1 Receptor, Chemosis
Document Summary
Anti-allergic: students will know how to advise their patients with allergic eye disease, students will know the mechanism for their supply decision. Allergic eye disease is thought to affect between 15 and 40% of the population (gomes 2014) and takes the form of two main types, perennial allergic conjunctivitis (pac) and seasonal allergic conjunctivitis (sac). As the name suggests, perennial is not season dependant whereas seasonal is! Sac would commonly be called hay fever and is due to a immunoglobulin e (ige) hypersensitivity reaction to pollen. Pac is due to a ige hypersensitivity reaction to a range of allergens, such as animal dander, mould spores or house dust mites. Most cases of allergic conjunctivitis are seasonal and present in spring or early summer. Allergic conjunctivitis is caused by an immunoglobulin e (ige) response to an allergen. Allergens bind to mast cells in the conjunctiva causing them to degranulate, which initiates an inflammatory cascade.
