DANCEST 805 Lecture Notes - Lecture 39: Rheumatoid Arthritis, T Helper Cell, Lymph Node
Document Summary
Immunotherapy: rheumatoid arthritis, cancer immunotherapy, transplantation, 80% of lung, liver and kidney recipients now survive. Edward jenner founded the field of immunology and termed the procedure vaccination from the latin for cow pox which he used to vaccinate against small pox. One organism benefits and the other one is unaffected. One organism benefits at the expense of the other. Pathogens: most bacteria in the body are commensal organisms, there are 10x more bacteria than human body cells, play important role in fermentation, digestion and absorption of nutrients, causes disease. Antigen: a molecule capable of inducing an immune response: not always derived from microbe, not all microbes have antigens, not all of us see the same substances as antigens. Protection against pathogens: mucosal barrier (physical, skin, respiratory tract, intestines, innate immune system, immediate and acts within minutes, recognises foreign pathogens via germ-line encoded receptors.
