CRIM 12000 Lecture Notes - Lecture 9: Orbitofrontal Cortex, Striatum, Prefrontal Cortex

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Impulsivity and adhd (attention deficit and hyperactivity disorder) are perhaps. 75% genetically based: variations in the ar gene are associated with violent crime, caspi and trembly studies. Caspi study: abused/insufficient nurturing + genetically vulnerable = 85% developed anti-social behaviors: abused/insufficient nurturing + no genetic vulnerability = virtually no anti-social tendencies, not abused/sufficient nurturing + genetic vulnerability = virtually no anti-social tendencies. Behavior impacted by (trembly thesis is that the 66% figure will drop even further as time passes) Insufficient brain development/brain abnormalities continued: high norm compliance individuals: high activity in the lateral orbitofrontal cortex and right dorsolateral prefrontal cortex (areas not developed until early. Lead, cadmium, mercury, pcbs (heavy metals: sugar/hypoglycemia, manganese, hcd (hexachlorobenzene, prenatal nicotine exposure. Nutritional deficiencies/orthomolecular deficiencies: general vitamin and nutritional deficiencies, prenatal protein deficiencies, cholesterol deficiencies, zinc deficiencies, fatty acid deficiencies (omega 3, omega 6, dha, vitamin b and chromium deficiencies. Insufficient brain development/brain abnormalities: externally sourced origins:

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