AN S 345 Lecture Notes - Lecture 6: Citric Acid Cycle, Oxidative Phosphorylation, Muscle

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Mesodermal progenitor cells myoblasts early myotubes mature myotubes muscle fibers muscle transcription factors that enable an ease of muscle synthesis a direct link to the type of tf turned on and what event in myogenesis that will occur next. Key concepts : glycolysis, tca cycle electron transport chain. oxidative phosphorylation. Glycolysis in the cytoplasm citric acid cycle in the mitochondrial/ electron transport chain -- krebs cycle [tca] is the primary energy source to drive oxidative phosphorylation. Catabolic reactions and anabolic reaction absorption is mostly mitochondria synthesis is mostly in the cytoplasm. Krebs cycles can produce intermediates that exit mitochondria and go to other pathways important to metabolism. Cell is tricked by the concentrations and now there is more passive uptake of glucose by the cell from glycolysis we get a net yields of 2 atp and an ending product of pyruvate, acetyl. When an animal is in a positive energy balance we actually saturate the krebs cycle.

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