RIU 435 Lecture 4: High Risk Pregnancy Pt 1

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Recognize the maternal and fetal factors for high risk. Interpret role of the sonography in evaluation and managing of high risk pregnancies. Maternal risk factors vs fetal complications of pregnancy. 3rd trimester bleeding- in 3-4% of pregnancies. Advanced maternal age disorders of fetal growth. First trimester testing - looks for the pattern of biochemical markers associated with plasma protein a (papp-a) and free beta- hcg3. Quad screen- looks at following serum markers: Targeted ultrasound- is detailed evaluation of all fetal anatomy seen at time of exam. Fragments of fetal dna in maternal blood. Cvs is us directed biopsy of placenta or chorionic villi. Chorion frondosum is active trophoblastic tissue that. More cells are obtained than in amniocentesis= faster result. Because chorionic villi fetal in origin, chromosomal becomes the placenta abnormalities may be detected when cells from villi are grown and analyzed. Can be performed between 9 and 12 weeks. Risk of complications is higher than amniocentesis.

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