PSYC 372 Lecture Notes - Lecture 8: Neural Tube Defect, Radial Glial Cell, Spina Bifida
Document Summary
Neurodevelopment: the nervous system develops from a few dozen cells. Rapid changes occur during development, but continue to change throughout life: the human nervous system begins to develop 3~ weeks after conception, tasks to accomplish to be considered a fully functional nervous system. The embryo initially consists of 3 germ layers: ectoderm (outermost, mesoderm (middle, endoderm (innermost) The neural plate arises from ectoderm: will develop into the entire nervous system. Within a few days, ends of the neural plate join to form the neural tube: spina bifida: a neural tube defect; incomplete closure of the neural tube, risk reduced by folic acid supplementation. Inside of the neural tube becomes the cerebral ventricles, and central canal. Neural tube bends and swells to form the three-major brain division (forebrain, midbrain, hindbrain) by 40 days post-conception: neural proliferation. Once the neural tube has formed, its cells begin to divide (proliferate: mainly occurs in the ventricular zone (the inner surface of the neural tube)