BIOL 3600 Lecture 12: 4 October - Genetic Drift and Tests of Selection II

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10 Oct 2018
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Gene trees and coalescence: different copies of allele leave different numbers of descendants, looking back in time, gene lineages coalesce (converge) Effective population size: effective population size (ne) ~ idealized (haploid) population size that behaves same way with respect to drift as population of size n, expected heterozygosity (theta) = 4neu. Fischer"s fundamental theorem of natural selection: rate of increase in fitness of any organism at any time is equal to tis genetic variance in fitness at that time. Selection gradients: selection gradients ~ measure strength of selection acting on trait when effects of all other traits are held constant. Heritability: heritability ~ measures parent- offspring correlations. Breeder"s equation: deltaz = h^2s, z: mean value of trait, delta z: change in value of trait. Natural selection and genetic drift are the two most important causes of evolutionary change. A large population of 3 spined stickleback fish lives in alaskan lake.

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