BIOL 123 Lecture Notes - Lecture 8: Heritability, Population Genetics, Outcrossing
Document Summary
Population genetics is like shuffling and dealing cards. With random mating, sex-chromosome genes that start out at different frequencies move toward the same frequency. When you cross the male and female offspring, the males get the x entirely from the mother, where the females get the average allele variation from each parent. This also holds for a whole population. If you start at a point where the allele frequency is different for each parent, after random mating, the frequency will change. Takes multiple generations to get to equilibrium of alleles. Recombination progressively breaks down nonrandom associations of alleles among loci. This is a process similar to that of starting with nonrandom combinations of cards among hands in poker or bridge and then shuffling the cards repeatedly. Inbreeding is a bad thing in normally outbreeding natural populations. Bad for homozygous mutations, that appear in family will appear more frequently.
