BIOL 102 Lecture Notes - Lecture 23: Jenny Mccarthy, Xyy Syndrome, Andrew Wakefield

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4 Jan 2021
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Nondisjunction = gametes having too many or too few chromosomes due to errors in meiosis: can affect the number of either sex chromosomes or autosomes. Most embryos that arise from the fusion of gametes with abnormal chromosome numbers spontaneously abort, accounting for 20%-50% of all miscarriages, but some survive to birth and beyond. Some genetic disorders are caused by abnormal numbers of sex chromosomes. Nondisjunction of sex chromosomes in males produces sperm with either no sex chromosome (often called o sperm), or two sex chromosomes (the sperm may be. Xx, yy, or xy, depending on whether the nondisjunction occurred in meiosis i or. Nondisjunction of the sex chromosomes in females produces o or xx eggs instead of eggs with one x chromosome. When normal gametes fuse with these defective sperm or eggs, the zygotes have normal numbers of autosomes but abnormal numbers of sex chromosomes. The most common abnormalities are xo, xxx, xxy, and xyy.

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