MCB 3020 Lecture Notes - Lecture 18: Ribosomal Rna, Messenger Rna, Transfer Rna

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26 Feb 2017
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All dna present in a cell or virus. Bacteria and archaea generally have one set (haploid 1n) Eukaryotes have two sets (diploid - 2n: genotype. Specific set of genes an organism possesses: phenotype. Dna as genetic material: griffith in 1928 observed the change of non-virulent organisms into virulent ones as a result of (cid:862)tra(cid:374)sfor(cid:373)atio(cid:374)(cid:863, macleod and mccarty in 1944 showed that the transforming principle was because of dna. Dna and rna structure: the nucleic acids, dna and rna, are polymers of nucleotides linked together by phosphodiester bonds, dna and rna differ in the nitrogenous bases they contain the sugars they contain. Whether they are single or double stranded. Contains the bases adenine, guanine, cytosine, and uracil. Phosphodiester bonds: most rna molecules are single stranded; some are double stranded, three different types which may differ from each other in function, site of synthesis, and in structure. Messenger rna (mrna) ribosomal rna (rrna) transfer rna (trna)

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