NBB 301 Lecture Notes - Lecture 13: Postsynaptic Density, Enzyme, Dendritic Spine

• School: Emory University
• Department: Neuroscience & Behavioral Sci
• Course: NBB 301
• Professor: Frenzel Kristen

Document Summary

Www. mcb80x. com : potentiation and depression: potentiation and depression overview, potentiation: increase in synaptic strength, depression: decrease in synaptic strength, synaptic plasticity: gives us the ability to learn from our experiences. Glutamate, glycine, nmda, ampar, d-serine: donald he(cid:271)(cid:271): neurons that fire together, wire together while neurons that fire out of syn(cid:272), lose their link. Increased probability of presynaptic neurons releasing nt in response to presynaptic. Synaptic potentiation/ facilitation -- due to increased nt (increase epsp) Hebbian: classic: neurons that fire together are wired tgt, nmda-dependent ltp, nmda receptor = special glutamate receptor non-hebbian ltp, explicitly anti-hebbian forms of ltp. Hebbian ltp: when pre and postsynaptic neurons fire tgt. ** nmda and ampa are not natural occurring molec but were synthesized and found to bind to these receptors so were named as such. Input specificity: affects only certain synapses, not all. Associativity: when weak stimulation of single input is insufficient for the induction of.