HLTH 210 Lecture Notes - Lecture 6: Headache, Aspirin, Southeast Asia
23 Mar 2018
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Document Summary
Acute respiratory infection caused by highly contagious rna virus belonging to the (acute febrile respiratory illness) Types a, b, c (a and b most important) Type a most deaths, can cause pandemics. Ha adheres to human respiratory epithelium through residues. All ha and na affects/infects birds (avian virus/ poultry) Influenza virus are highly susceptible to antigenic shifts and drifts. Antigenic drift: mutations of virus as it gets passed from bird ---> humans/pigs rearrangement. Point mutations in the ha and/or na gene. Continuous development of new strains secondary to genetic mutations/seasonal epidemics. Emergence of a new human influenza a virus subtype (new ha subtype) through: genetic reassortment (human and animal viruses) and direct animal (poultry) to human transmission. A pandemic can occur if: efficient and sustained virus transmission occurs among humans (sustained person to person spread) A pandemic can result in: widespread morbidity and mortality worldwide. High proportion of deaths among young adults.
