BIOSC-116 Lecture Notes - Lecture 30: Cytokinesis, Nucleolus, Microtubule

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Sister chromatids attach to microtubules at kinetochore. Sister chromatids face opposite poles, then separate at centromere, and move to poles. Somatic cells that cannot pass genetic material to future generations: diploid in humans, make up vast majority of individual"s tissues, mitotically divide. Germ cells that can pass genetic material to future generations: produce gametes (sperm/egg, incorporated into ovaries and testis, undergo meiosis, gametes are haploid. Prophase 1 longest phase: 5 substages: leptotene, zygotene, pachytene, diplotene, and diakinesis. *centromere and kinetochore stay together during meiosis 1* Pair, recombine genetic material, segregate into 2 separate nuclei. Centrosomes begin to move to each pole and produce spindle fibers. Homologous chromosomes zipper together in an intimate association (synapsis) Synapsis cleaves dna molecules and rejoins it. Allows for transfer of maternal/paternal dna exchange. Crossing over, genetic exchange between nonsister chromatids of a homologous pair. Recombination nodules appear along the synaptonemal complex: nodules facilitate the exchange dna at various points.

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