BIOSC-101 Lecture Notes - Lecture 11: Interphase, Chromosome, Covalent Bond

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The presence of two strands accounts for the double helix of dna. Antiparallel - their subunits run in opposite directions. Adenine and guanine are purines (double ring) Cytosine and thymine are pyrimidines (single ring) Dna structure & function you should be able to: Watson and crick introduced the double-helical model for the structure of dna. Because a purine + purine would be too wide and a pyrimidine + pyrimidine would be too narrow. Adenine forms 2 hydrogen bonds with thymine and only thymine. Guanine forms 3 hydrogen bonds with cytosine and only cytosine. A key feature of all nucleic acids is that they have two distinctive ends: the 5" (5- prime) and 3" (3-prime) ends. The two strands are held together by hydrogen bonds (between base pairs) Describe the process of dna replication; include the following terms: antiparallel structure, dna polymerase, leading strand, lagging strand, okazaki fragments, Dna ligase, primer, primase, helicase, topoisomerase, single-strand binding proteins.

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