NEUROSCI 101 Lecture Notes - Lecture 14: Thalamus, Sensory System, Time Perception
8 Mar 2016
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Notes: circadian: suprachiasmatic nuclei (scn) of hypothalamus, melatonin, interval timing: basal ganglia and cortex, greater than 1s, up to couple of hours, millisecond timing: cerebellum, motor. Interval and millisecond timing are related b/c motor functions. Examples: sleep, awake, lowest body temp, highest blood pressure. Use animals with strong daily activity cycles (hamsters/mice) Wheel running activity actograms: sensors on a running wheel that calculates revolutions, see activity of animal at different times throughout the day, line up the daily activity histogram-like graph. Activity entrains to light entrained to light cycle (exogenous: good rhythm, more activity during dark cycles for nocturnal animals. Exogenous: external cue that promotes cycles, etc. Endogenous: no external cue to promote cycle, etc. Tau = natural running/endogenous cycle, often just outside of 24hrs: smaller: waking up earlier each day, greater: waking up later each day. Zeitgeiber: anything that is able to set circadian rhythm/clock (ex: light) Humans also have light and free-run cycles, too.
