EBIO 1210 Lecture Notes - Lecture 16: Dna Polymerase Iii Holoenzyme, Start Ii, Dna Ligase
13 Nov 2016
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Document Summary
Dna polymerases: match the right monomers with the template, catalyze formation of new sugar-phosphate bonds, add 50 (eukaryotes) to 500 (bacteria) bases per second. The lagging strand is synthesized as a series of fragments. Based upon the semiconservative model, which is true about the dna molecules contained by sister chromatids present in. G2 phase: b and c, each sister chromatid has a double-stranded. Dna molecule: each sister chromatid has a strand of dna from the original dna molecule paired with a newly synthesized strand. In dna replication, the difference between the leading strand and the lagging strand is that: synthesis of the lagging strand begins after synthesis of the leading strand is complete. Consequences of linear chromosomes and the requirements of dna polymerase. Gradual shortening / erosion of dna in most of our cells as divisions go on throughout our lifetimes.
