BIOL 031 Lecture Notes - Lecture 3: Sodium Chloride, Erythropoietin, Molality
Document Summary
Intracellular fluid: of total, inside of cells. Extracellular fluid: of total, both plasma and interstitial fluid. Plasma: of ecf (1/12 of total fluid) Interstitial: of ecf ( of total fluid) Donnan effect: plasma proteins negatively-charged but can"t leave vessels, so pull more positive ions into the plasma (more negative ions in the interstitium) Understand the different types of membrane transport phenomena and the driving forces governing movement of water, ions and solutes across membranes. Driving force: chemical gradient (diffusion pressure) + electrical gradient (membrane potential) Net: electrochemical gradient (forces can act in same or opposite directions) Free-moving: small, uncharged nonpolar, dissolved gases, small uncharged polar. Need transport proteins: water, charged ions/molecules, larger molecules. Passive transport: simple diffusion or facilitated diffusion (using transporters) Active transport: uses energy from atp hydrolysis. Secondary active transport: uses potential energy from. Understand the types and molecular mechanisms of membrane transport proteins concentration gradient of another ion including channels, transporters and pumps.