BIOL 030 Lecture Notes - Lecture 32: Distal Convoluted Tubule, Proximal Tubule, Nephron

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The kidney is made up of millions of functional units, known as nephrons. These units filter the blood and produce urine. The nephron is composed of the glomerulus and renal tubule. Consists of a bundle of capillaries enclosed within the glomerulus capsule (bowman"s capsule) This capsule creates space between the capillaries and its walla called the capsular (bowmans) space. Blood flows into the glomerulus and through the capillaries. Filtration occurs when components of the blood are removed from the capillary into bowman"s space. The material in the bowman"s space is known as filtrate. The vascular pole, serves as an entry/exit for capillaries within bowman"s space. The urinary pole, serves as an exit for filtrate into the renal tubule. The capillaries of the glomerulus are fenestrated, or have small holes, allowing ions, water, and other molecules to move through their membranes as filtrate.

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