BIOL 030 Lecture Notes - Lecture 23: Neural Tube, Lateral Plate Mesoderm, Scoliosis
16 Sep 2020
School
Department
Course
Professor
Document Summary
Understand how mesoderm and neural crest contribute to skeletal system formation. Understand the basic processes involved in development of the axial skeleton. Understand the principal molecules and genes involved in somite differentiation that relate to skeleton development. Describe how vertebrae and ribs are formed by endochondral ossification of sclerotome regions of somites. Understand the principal molecules and genes involved in development of vertebral column. What are brevicollis, spina bifida, and scoliosis; what are some of the causes for these defects. Describe how ribs form from lateral processes of thoracic vertebrae. Describe how the sternum and clavicle are formed. Understand the basic processes involved in development of the appendicular skeleton. Describe how somatic lateral plate mesoderm forms the skeleton of the appendages the limb bones and appendicular girdles. Describe how the appendicular skeleton is formed by endochondral ossification of cartilage models.
