ACCT 210 Lecture Notes - Lecture 33: Leishmania Major, B Cell, Coinfection

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Co-evolution travelling less immunity hence worse pathology. Us investment in malaria wwii, korea, vietnam. Parasite: lives / feeds on / in different species > detrimental to host. Viruses / bacteria / ectoparasites may also be considered so, but not here. Direct: single definitive host, site of sexual cycle: but will always have external stage, worms / protozoa- eggs need to get out can"t live entirely within host. Indirect definitive plus intermediate host(s: also invertebrate vectors not extended host exploitation, multiple hosts multiple criteria for selection hence differing morphology adaptive, multiple developmental stages > diverse pathologies from single species. Properties: flexibility eukaryotic large genomes, organelles, life cycles developmental stages adaptive to host environments (inter and intra, single species range pathologies, long lived capable cryptic / chronic. Animals not far from humans; metazoans: multicellular co-evolution w. host, maintain host health long enough > cycle completion propagation, transmission, not normal host bad.

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