NS 1150 Lecture Notes - Lecture 5: Carbohydrate, Ghrelin, Helicobacter Pylori
2 Sep 2016
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Pyloric sphincter: acts the same as esophageal sphincter but keeps it inside the stomach. Treatment gerd: reduce the acidity with acid buffers, bicarbonate (alka-seltzer, acid blockers, pepto bismol (bismuth, h2 blockers (tagamet, zantac, proton pump inhibitors (ppi) c. i. c. ii. Problem when you stop (rebound hypoersecretion: avoiding foods (secretogogues) and drugs that release gastrin (aspirin, ibuprofen, smoking, alcohol, coffee, hot spices, prevents heartburn n shit, sleeping vertically. Cephalic stage: mucous secretion, gastrin b. i. b. ii. Released by stretching wall by food bolus: gastrin releases c. i. Safe form of pepsin: normally, pepsin will break down cell membrane of the body too: gastric ulcers, causes of gastric ulcers a. i. Prevents cells from secreting mucous a. ii. a. iii. a. iv. First treatment for ulcers is antibiotic: stomach secretions, gastrin -> acid, pepsinogen -> pepsin, gastric lipase, ghrelin d. i. d. ii. d. iii. Secretion stimulated when empty: determinants gastric emptying, volume, osmotic pressure b. i. b. ii. Reduced by fluid entering from blood: acidity c. i.
