NS 1150 Lecture Notes - Lecture 35: Esophageal Cancer, Low-Density Lipoprotein, Adipose Tissue

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Sodium reduction results in significant decrease in bp. Significant increase in plasma renin, plasma aldosterone, plasma adrenaline, and plasma noradrenaline (sympathetic), ldl cholesterol, and triglyceride (maybe not beneficial) Results do not support that sodium reduction may have net beneficial effects in a population of caucasians. Major predictor of: heart attack, stroke, retina failure, kidney failure (sensitive to bp) Two types of hypertension: essential (primary) May be related to atherosclerosis: secondary. Two essential measurements: systolic pressure (peak/upper value) Other indicators that are significant determinants for bp: less we make, higher incidence of elevated blood pressure, costly, health disparities. Factors associated with hypertension: alcohol > 3 oz. per day (>2 oz. mouth and esophagus cancer risk increases, diet. High saturated fat (therefore body weight and location of weight) High in lead, cadmium, zinc, mercury: crowding. Number of interactions (moving to urban areas increases bp: abdominal fat. Location of fat deposit as you get older.

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