BIOMG 1350 Lecture Notes - Lecture 3: Protein Folding, Hydrogen Bond, Titin

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Chemicals: inorganic ions, small molecules, phospholipid, dna, rna, protein, polysaccharide. Macromolecules are made of relatively few types of atoms. Macromolecules are polymers constructed from a limited number of subunits. Sugar and polysaccharide, amino acid and protein, nucleotide and nucleic acid. Attached to an amino group, carboxyl group, hydrogen and r side chain. All 20 amino acids are identical except for the r group. At ph 7 , both amino and carboxyl groups are ionized. Amino acids are linked together by peptide bonds. Condensation reaction: water is formed as product of reaction. Polypeptide backbone always the same, only side chains different. Proteins fold into unique structure: every single molecule of the same protein will fold the same way and look the same and have the same structure. Proteins work by interacting with other things in the cell. Conformation of a protein is determined solely by its amino acid sequence.

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