BIOMG 1350 Lecture Notes - Lecture 8: Sodium-Potassium Alloy, Tandem Pore Domain Potassium Channel, Cytosol
1 Nov 2016
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Quote of the day: oh yeah that"s right i"m doing me. -drake. Lipid bilayers block the passage of most water-soluble molecules. Small nonpolar molecules can go through (o2, co2, n2, steroid hormones) Small uncharged polar molecules may go through (less likely) Large uncharged polar molecules very unlikely to go through (amino acids, Transport proteins move water soluble-molecules across membranes glucose, nucleotides) Channels: a specific opening, or pore, that allows certain ions through. Fast: ions can flow through whenever open, like a door. Transporters: undergo conformational changes to transport molecules through, very specific protein binding site. Slower: like turnstile due to conformational change. Uses concentration gradients = energetically favorable (stats) Interior of cell is more negative than outside of cells. Charged molecules will respond not only to concentration gradient but voltage gradient. Conc gradient and volt gradient can work together or work against each other. Transporters can do both passive and active. Three stages (open to outside, closed, open to inside)
