Log in
HomeClass Notes1,200,000US530,000

BIOMG 1350 Lecture Notes - Lecture 12: Radiography, Cdk Inhibitor, Peptide

22 views3 pages
School
Cornell University
Department
Molecular Biology and Genetics
Course
BIOMG 1350
Professor
Discussion

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

Duration of cell cycle varies depending on type of cells. Cytokinesis (cytoplasmic division) at the end of mitosis. Rest of the cell cycle: interphase (cannot be seen under microscope) Concentration varies (cycles) during the cell cycle. Distinct cdks associate w different cyclins to trigger different events of the cell cycle. M-cdk protein is always there, but the activity level varies. The m-cyclin concentration grows/falls depending on mitosis stage. Just because cyclin is going up, the m-cdk is not necessarily activated that early. M-cdk is regulated by inhibitory and activating phosphorylations. After m-cdk is attached to m-cyclin, must be phosphorylated in 2 spots. Activating kinase (cak) adds an activating phosphate. Activating phosphatase (cdc 25) removes the inhibitory phosphate to activate m-cdk. Positive feedback provides a steep rise in m-cdk activity. Active m-cdk will activate more inactive cdc 25, which will in turn activate more m-cdks. Active m-cdk also phosphorylates wee1 (inhibitory) which inhibits the inhibitory which stops that activity.

Get access

Grade+
$40 USD/m
Billed monthly
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
10 Verified Answers
Class+
$30 USD/m
Billed monthly
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
7 Verified Answers

Related Documents

BIOMG 1350 Lecture Notes - Lecture 18: G1 Phase, G2 Phase, Spindle Apparatus
fuchsiadog160
BIOMG 1350 Chapter Notes - Chapter 18: Sister Chromatids, Motor Protein, Actin
fuchsiadog160
BCHM 2021 Lecture Notes - Lecture 1: Cdk Inhibitor, Sister Chromatids, Spindle Apparatus
chocolatemole27

Related Questions

Part A:

In prokaryotes and eukaryotes cell reproduction is similar in that it requires some kind of signal to proceed, DNA replication, careful separation of the DNA into two equal portions, and division of the cytoplasm. How is cell reproduction different in prokaryotes and eukaryotes?

Select one:

a. In a eukaryotic organism, the signals for cell division are usually not related to the environment but to the function of the entire organism.

b. Eukaryotic cells constantly divide whenever environmental conditions are adequate and the cells are large enough.

c. The linear chromosomes in prokaryotes are constantly being updated.

d. Prokaryotic cell division requires cytokinesis before mitosis because of their small size.

e. The sexual phase of most prokaryotes (bacteria) is essential to the rapid cell division required for infection.

Part B:

What does the name Cyclin Dependent Kinase stand for?

Select one:

a. A protein important to the cell cycle that is dependent on DNA synthesis.

b. An enzyme that cuts DNA so that chromosomes can segregate.

c. An enzyme that phosphorylates other proteins using ATP only when the protein Cyclin is bound to the enzyme.

d. An enzyme that rolls along microtubules dragging a vesicle.

e. An enzyme that connects chromosomes to the spindle fiber.

Part C:

The Cell Cycle is divided into Mitosis, Cytokinesis, and Interphase. Mitosis can be ordered into the following phases:

Select one:

a. Prophase/Prometaphase/Metaphase/Anaphase/Telophase

b. Anaphase/Prometaphase/Metaphase/Prophase/Telophase

c. Metaphase/Anaphase/Telophase/Prophase/Prometaphase

d. Telophase/Prophase/Prometaphase/Metaphase/Anaphase

e. Anaphase/Telophase/Prophase/Prometaphase/Metaphase

Part D:

The Cell Cycle is divided into Mitosis, Cytokinesis, and Interphase. Interphase can be ordered into the following phases:

Select one:

a. S/G1/G2

b. G2/G1/S

c. G1/S/G2

d. G2/S/G1

e. G1/G2/S