BIOMG 1350 Lecture Notes - Lecture 6: Histone H1, Nucleosome, Histone H2A

• School: Cornell University
• Department: Molecular Biology and Genetics
• Course: BIOMG 1350
• Professor: Discussion

Document Summary

Quote of the day: made the beat then murdered it, casey anthony. -childish gambino. In solution, they exist as rings, not chains. Monomers linked together through condensation reaction (h2o is released) Difference between ribose and deoxyribose is the absence of an oxygen in deoxyribose (oh group vs h) 6 member ring, 4 carbon and 2 nitrogen. Different side chains: u = carboxyl group, thymine = methyl. Guanine = carbonyl and amine group, adenine = just amine group. 5" is at the bondage between phosphate and sugar. 3" is at the sugar end of the chain (oh-) 2 bonds that hold at bonds, 3 bonds that hold gc bonds. One side goes 5" to 3", and the other is in reversed direction. Most protein interactions in major groove due to larger size. Dna is negatively charged due to phosphate groups. Dna polymerase added a deoxynucleotide to the 3" end of a growing dna chain.