BIOG 1440 Lecture Notes - Lecture 4: Liposome, Competitive Inhibition, Allosteric Regulation
6 Feb 2017
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Pre-class for wednesday - should be anaerobic not aerobic. An artificial liposome, whose membrane contains no proteins is loaded with a 0. 03 m sucrose solution and put into pure water. Metabolism is the totality of an organism"s chemical reactions. Catabolic - generate energy, anabolic - requires energy. Enzymes speed up reaction by lowering energy barriers. G < 0, the free energy in the products is lower than that of the reactants. The active site on an enzyme is where the substrate binds. Induced fit of substrate brings chemical groups of the active site to enhance hte ability catalyze the reaction. How does substrate binding lower e a covalently bonding to the substrate. Orienting substrates, straining substrate bonds, providing favorable micrenivornment, Food preservation (mentioned salt) changing ph also helps. Dpp + paba product (step we"re focusing on) Why don"t sulfonamides affect humans? (folic acid is b 9 ) involved in dna synthesis.
