BIOG 1440 Lecture Notes - Lecture 2: Abo Blood Group System, Malaria, Glycoprotein

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Describe critical roles of proteins (in cellular physiology) Properties: selective permeability (some things cross more easily than others) Water moves on either side of the bilayers, but not in the middle. Inside membranes are cytosol or cytoplasm ph is usually different inside. Given the selectively permeable nature, there can be gradients across the bilayer. Selectively permeable - just lets through water. Amphipathic - applies to membranes and proteins (contains hydrophobic and hydrophilic regions) Membrane - hydrophilic head groups (towards outer surface) and hydrophobic tails (toward the inside) Hydrophobic tails are usually fatty acids, but not always. Kink in fatty acids - represents a double bond (important!) Ether lipids, long molecules that cross the whole membrane. Fluid mosaic model - fluid w/ mosaic of proteins embedded in it. Take a protein, add green protein to it. Cannot regain fluorescence, so recovered area is by diffusion. Some proteins are anchored - so cannot diffuse.

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