LIFE 102 Lecture Notes - Lecture 11: Noncoding Dna, Systems Biology, Genome Size
Document Summary
Provide information about the evolutionary history of genes and taxonoic groups. Genomics : is the study of who sets of genes and their interactions. Bioinformatics is the application of computational methods to the storage and analysis of biological data. The rate of genomic sequencing has dramatically increased while costs have decreased. Identification of protein-coding genes within dna sequences in a database. The comparison of sequences of previously unknown genes with those of known genes in other species may help provide clues about their function. Dna from a group of species (a metagenome) is collected from an environmental sample and sequenced. The technique has been used on microbial communities, allowing the sequencing of dna of mixed populations and eliminating the need to culture species in the lab. Proteomics is the systematic study of all proteins encoded by genome. Proteins, not genes, carry out most of the activities of the cell. Systems biology integrates complex interactions between the components of whole organisms.
