LIFE 102 Lecture 23: Chapter 15-Day 3
Document Summary
Indicate the positions of genes with respect to chromosomal features. Alterations of chromosome number or structure cause some genetic disorders. Large-scale chromosomal alterations often lead to spontaneous abortions (miscarriages) or cause a variety of developmental disorders. Pairs of homologous chromosomes do not separate normally during meiosis. As a result, one gamete receives two of the same type of chromosome and another gamete receives no copy. Results from the fertilization of gametes in which nondisjunction occurred. Offspring with this condition have an abnormal number of a particular chromosome. Has only one copy of a particular chromosome. A condition in which an organism has more than two compete sets of chromosomes. Breakage of a chromosome can lead to four types of changes in chromosome structure: Moves a segment from one chromosome to another. Certain cancers, including chronic myelogenous leukemia (cml), are caused by translocations of chromosomes. *alterations of chromosome number and structure are associated with some serious disorders.
