LIFE 102 Lecture Notes - Lecture 22: Genetic Linkage, Centimorgan, X-Inactivation

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31 Oct 2016
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Some disorders caused by recessive alleles on the x chromosome in humans: In mammalian females, one of the two x chromosome in each cell is randomly inactivated during embryonic development. If a female is heterozygous for a particular gene located on the x chromosome, she will be a mosaic for that character. *linked genes tend to be inherited together because they are located near each other on the same chromosome. *each chromosome has hundreds or thousands of genes. Genes located on the same chromosome that tend to be inherited together. Morgan did other experiments with fruit flies to see how linkage affects inheritance of two characters. Morgan crossed flies that differed in traits of body color and wing size. *morgan found that body color and wing size are usually inherited together in specific combinations. The production of offspring with combinations of traits differing from either parent. Offspring with a phenotype matching one of the parental phenotypes.

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