NUTR-4550 Lecture Notes - Lecture 3: Glycolysis, Autophagy, Glut2
Document Summary
Lecture 3: fuel utilization in response to food intake. Duct cells in the pancreas release bicarbonate and other digestive enzymes. A-cells produce and release glucagon: glucagon is a catabolic hormone since it signals the breakdown of stored nutrients. Slide 2: how the body stays in glucose homeostasis. It will accept excess glucose and turn it into fatty acids and then triacylglycerols for storage. **glut4 is respondent to insulin concentrations in the blood. In regular conditions, a few glut4 molecules will implant in the membrane. Glut4 will implant in the membrane to allow glucose into the cell (this also signals the nucleus of the cell to begin production of more glut4 transporters. **glut2 typically has constant use whether glucose is abundant in the blood stream or not it is one of the main transporters for glucose. Understand the trends for each hormone: high glucose=high insulin=low glucagon, low glucose=low insulin=high glucagon.
