CAS PS 544 Lecture Notes - Lecture 16: Inhalant, Peer Pressure, Adh1B
17 Dec 2016
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It makes more economic sense to give education/treatment than imprison: prison is a thriving business, hard to get elected if you support this. Alcohol use disorders: by eighth grade 25% have been drunk. Early onset drinking has been seen to have higher suds: alcohol problems: intergenerational factors. Children of alcoholics 4-5 times more likely to develop alcoholism (still only. Family transmission of alcohol/substance problems appear to be general, the trait of behavioral disinhibition: genetics of substance problems: adoption studies. Twin and adoption evidence for vulnerability to alcohol/substance dependence. Adoption study of risk factors for opiod dependence: Divorce and conflict in adoptive family (environmental: adh and aldh polymorphisms on alcohol metabolism: protective alleles. Genetic molymorphisms that affect how your body metabolizes alcohol. Adh1b*2 allele rapid ethanol conversion to acetaldehyde. More common in east asian and people of jewish descent. Aldh2*2 allele inactivates conversion of acetaldehyde to acetate. Common in east asians but extremely rare in people of european or.
