CAS NE 203 Lecture Notes - Lecture 5: Medial Lemniscus, Golgi Tendon Organ, Posterior Grey Column

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Tactile (touch, temperature, pain) and proprioception (knowledge of position of your body in space) Encapsulated nerve endings some respond to high/low frequency. Know pacinian, ruffini, meissner"s, merkel"s know receptive field, fast/slow adaptation: meissner"s/merkels smaller, closer to surface, pacinian/ruffini larger, deeper in dermis. Two-point discrimination: size of receptive field, how densely populated it is with neurons. Stress/strain: ruffini in fingers proprioceptive information. Coronal (crown), sagittal (right/left side), transverse (horizontal) Tactile dorsalcolumn mediolateral system, ascend via dorsal column, travel through medial lemniscus, vpl nuclei in thalamus to cortex via internal capsula: decussates in caudal medulla. Pain decussate right away, after traveling a bit through the spinal cord. Face trigeminal (cnv), 3 branches ophthalmic, maxillary, mandibular: decussate before the vpm, right after nucleus of trigeminal complex, go to vpm, go to facial areas of s1 (more lateral than other areas) Neocortex 6 layers, intracortical connections: most projections enter layer 4, brodmann"s areas (4), 1, 2, 3a, 3b.

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