CAS CH 203 Lecture Notes - Lecture 9: Claisen Condensation, Enol, Thioester

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2 Dec 2017
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Lecture 9 biochemical transformations i. carbon-carbon bond forming and cleaving reactions in biology (see the lexicon). Enzymes catalyze a limited repertoire of reactions and use the same reactions over and over again. The wealth of knowledge about organic reaction mechanism is directly applicable to biological transformations and provides an excellent foundation for thinking about the transformations that you will encounter in primary metabolism. I have handed out a lexicon of reactions found in biology. You will encounter examples of all of the reactions in this compendium over the course of this semester and next semester for those of you who take chemistry 5. 08. The most prevalent reactions will be introduced in the next few lectures and the rest will be introduced in the context of the metabolic pathways in which they are found. Prenyl transfer reaction: review of carbonyl chemistry. Iv: review of carbonyl chemistry, distinct carbonyl components of relevance in biology.

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