CAS CH 203 Lecture Notes - Lecture 5: Polysaccharide, Model Organism, Petri Dish
21 Sep 2017
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Cell biology lecture #5 (continuing lecture #4 notes) Cftr: the most common lethal inherited disease in caucasians, ~1:2500 newborns affected. Active transport can also be driven by ion gradients. Model of the cystic fibrosis transmembrane conductance regulator (cftr) An example of active transport that does not depend on atp: some molecules can be transported against their concentration gradients using energy from coupled transport of another molecule in the energetically favorable direction. Gradients established by na+-k+ and h+ pumps provide a source of energy for active transport: glucose transporters in the apical domain of intestine epithelial cells transport two. Na+ and one glucose into the cell: flow of na+ down its electrochemical gradient provides the energy that drives uptake of glucose against its concentration gradient. Transport channels can be classified based on their relative directions of transport. Material surrounded by buds off w/in cell intracellular vesicle area of plasma membrane: phagocytosis.
