BIOL 375 Lecture Notes - Lecture 2: Quantitative Trait Locus, Epistasis, Pleiotropy

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Lecture 2: molecular genetics and development: history of heredity, blending inheritance b. Example: giraffe: wiseman: he cut the tales of mice, but the offsprings would still have tales. However, they self-fertilize: it"s hard to control because they can both self-fertilize and cross fertilize. Ex: chromosome perspective: 50 dad, 50 mom; see figure: mendel"s 2nd law: law of independent assortment, each allele behaves independently of other genes during gamete formation. Ex: blonde and blue eyes: if dependent assortment: only 2 combinations, independent assortment: 4 combinations, alleles from different genes do not necessarily go together. They behave independently during meiosis: mendel"s law in ruffs: fig 4. 2a, s= dominant, codes for satellite males. s= recessive, codes for independent males, but court together to attract female attention. ss is most common genotype. Huge variation in behavior, coloration, size . all controlled by one gene: we can actually look at allele frequency and make serious predictions about mating.

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