BIOL 311 Lecture Notes - Lecture 16: Christian De Duve, Esterase, Hurler Syndrome

• School: Binghamton University
• Department: Biology
• Course: BIOL 311
• Professor: Vanbuskirk

Document Summary

Chris tia n de duve (1955) - re ce ive d nobe l prize for the dis cove ry of lys os ome s. Ce ntrifuge us e d to look a t orga ne lle s. A ll othe r orga ne lle s you s e e wha t it is firs t a nd find out wha t it doe s s e cond - this wa s re ve rs e. Lys os ome s a re hydrolytic e nzyme s >40. Ie . prote a s e s , nucle a s e s , glycos ida s e s , phos pha ta s e. Lys os ome s ha ve e nzyme s ne ce s s a ry to cle a ve mos t norma l prote ins. Optimum ph is 5. 0 (whe re it pe a ks )