BIOL 118 Lecture Notes - Lecture 8: Conformational Change, Allosteric Regulation, Phosphorylation

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8 energy and enzymes: an introduction to metabolic pathways. Ke is energy of motion and molecular level is thermal energy. Pe is the energy of position or configuration. Free energy is the amount of energy available to do work. Chemical potential energy in cells, electrons are most important source. Amount of pe is based on its position relative to positive and negative charges. Electrons closer to negative charges and farther from positive charges have higher potential energy. Molecular potential energy is a function of electron configuration and position. First law of thermodynamics-energy is conserved: cannot be created or destroyed. Enthalpy is the total energy of a molecule represented by h. The pe of a molecule and the effect of the molecule on the surrounding pressure and volume. Changes in enthalpy are represented by deltah. Exothermic reaction releases heat and products have less pe than reactants. Endothermic reaction gains heat and products have higher pe than reactants.

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